• People who smoke less than 10 cigarettes per day.
  
• Adolescents (under 18 years of age).
  
• Pregnant and breast-feeding women.
  
• People with serious medical conditions (for example history of heart disease, chest pain, irregular heartbeat, recent heart attack, high blood pressure not controlled with medications, or take prescription medicine for depression or asthma).
  

Tobacco users in any of these groups should consult with a physician before using pharmacological treatment.
 

First-line Medications

The FDA has approved 6 medications:
download med chart

• Bupropion SR
• Nicotine gum
• Nicotine inhaler
• Nicotine nasal spray
• Nicotine patch
• Nicotine lozenge

Since there is not enough information to recommend one medication over the other, the choice of a specific first-line medication must be guided by factors such as:

• Clinician familiarity with the medication.
  
• Presence of contraindications.
  
• Patient preference.
  
• Previous patient experience with the medication.
  
• Patient characteristics (for example history of depression or history of seizures).

The first-line medications are the safest and most effective pharmacological therapies for the treatment of nicotine dependence.